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中华肩肘外科电子杂志 ›› 2026, Vol. 14 ›› Issue (01) : 29 -37. doi: 10.3877/cma.j.issn.2095-5790.2026.01.005

论著

反向全肩关节置换术治疗肱骨近端骨折内固定失败的疗效分析
孙懿贤1, 朱金雨2, 刘一超1, 孙鲁宁1,()   
  1. 1210029 南京中医药大学附属医院骨伤科
    2210029 南京中医药大学附属医院护理部
  • 收稿日期:2025-05-16 出版日期:2026-02-05
  • 通信作者: 孙鲁宁
  • 基金资助:
    国家自然科学基金面上项目(82474537); 江苏省中医院重点病种项目(YZB2418); 江苏省中医院科主任学术提升专项课题(Y2022ZR23); 南京中医药大学2024年科研与实践创新计划项目课题(SJCX240939)

Efficacy analysis of reverse total shoulder arthroplasty in the treatment of failed internal fixation of proximal humeral fractures

Yixian Sun1, Jinyu Zhu2, Yichao Liu1, Luning Sun1,()   

  1. 1Department of Orthopedics and Traumatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China
    2Department of Nursing, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China
  • Received:2025-05-16 Published:2026-02-05
  • Corresponding author: Luning Sun
引用本文:

孙懿贤, 朱金雨, 刘一超, 孙鲁宁. 反向全肩关节置换术治疗肱骨近端骨折内固定失败的疗效分析[J/OL]. 中华肩肘外科电子杂志, 2026, 14(01): 29-37.

Yixian Sun, Jinyu Zhu, Yichao Liu, Luning Sun. Efficacy analysis of reverse total shoulder arthroplasty in the treatment of failed internal fixation of proximal humeral fractures[J/OL]. Chinese Journal of Shoulder and Elbow(Electronic Edition), 2026, 14(01): 29-37.

目的

探讨反向全肩关节置换术作为翻修术式治疗肱骨近端骨折内固定失败的疗效。

方法

回顾性分析2018年4月至2023年11月期间收治的肱骨近端骨折钢板内固定失败患者9例,其中男2例、女7例;年龄51~76岁。9例均行反向全肩关节置换翻修手术。术前和术后系统性评估疼痛视觉模拟评分(visual analogue scale, VAS)、美国肩肘外科医师协会(American shoulder and elbow surgeons' form, ASES)评分、Constant-Murley肩关节评分量表、美国加州大学洛杉矶分校(University of California at Los Angeles, UCLA)评分、上肢功能障碍评定量表(disabilities of the arm, shoulder, and hand, DASH)、肩痛残疾指数(shoulder pain and disability index,SPADI)、关节活动度等关键指标,并分析手术并发症。

结果

9例均获得完整随访,末次随访与术前相比,前屈上举角度由(53.89±19.65)°增至(107.78±25.26)°;外旋角度由(3.33±9.68)°增至(31.67±6.61)°;内旋角度由(25.00±13.23)°增至(57.22±9.05)°;外展角度由(48.33±16.95)°增至(95.00± 15.00)°;UCLA评分由(9.33± 3.60)分增至(22.78±6.39)分;Constant-Murley肩关节评分由(23.44±5.70)分增加至(61.56±18.75)分;ASES评分由(34.11±9.66)分增至(74.44± 18.80)分;DASH评分由(65.55±9.13)分降至(31.73±11.05)分;SPADI评分由(57.34± 14.05)分降至(23.77± 16.35)分;VAS评分由(5.00±1.73)分降低至(1.11±2.26)分;且各项评分差异均具有统计学意义(P<0.05)。1例出现术后疼痛加重;1例术中出现肱骨干骨折。

结论

反向全肩关节置换术作为肱骨近端骨折内固定失败的翻修,具有可靠的疗效和良好的临床应用价值。

Background

Proximal humeral fractures (PHFs) refer to fractures involving the area from the humeral head to 2 to 3 cm away from the surgical neck of the humerus. They usually involve the surgical neck, large and small nodules, the anatomical neck, or the humeral head. Some patients also experience humeral head dislocation, and a few cases are accompanied by brachial plexus nerve injury. Epidemiological studies have shown that its incidence accounts for 4% to 10% of all fractures. Among elderly patients, its incidence rate is second only to hip fractures and distal radius fractures, and it is the seventh most common type of fracture in adults. With age, the phenomenon of osteoporosis, driven by physiological and pathological changes such as negative calcium balance and the degeneration of bone tissue microstructure, becomes increasingly evident. At the same time, the elderly often have geriatric syndromes such as ataxia and muscle strength decline, which can lead to PHFs when they suffer from low-energy injuries (such as falls, etc.). For stable fractures without obvious displacement, satisfactory therapeutic effects can be achieved through non-surgical methods such as suspension fixation and early functional exercise. However, for complex fractures with significant displacement, surgical treatment is usually adopted. There are numerous fixation techniques for PHFs. Dimakopoulos et al. believe that the bone suture fixation technique balances efficacy and cost-effectiveness. The Picker-needle fixation technique can prevent further damage to soft tissues and blood supply to the humeral head, but its success depends on satisfactory closed reduction, sufficient bone strength, minimal fragmentation, and good patient compliance. Intramedullary nail technique has good clinical efficacy and can provide more stable internal fixation, but discontinuous lateral cortical fragmentation is one of its major contraindications. Plate screw internal fixation is now one of the most commonly used surgical treatment methods for PHFs in clinical practice, with both traditional and locking plates available for selection. Locking plate internal fixation offers good angular stability and axial support and has gradually become the mainstream surgical treatment method for PHFs in recent years. Precise reduction of fracture fragments can be achieved through open reduction and internal fixation. However, the biomechanical stability of this technique significantly depends on sufficient bone mass support at the proximal end. For elderly patients with severe bone mass deficiency and poor blood supply at the fracture end, the locking plate internal fixation is very likely to fail, and the incidence of surgical complications has remained high. The main reasons for the failure of PHFs internal fixation include loosening of internal fixators, nonunion of fractures, necrosis of the humeral head, and secondary shoulder joint dysfunction. The management strategies for failed PHFs internal fixation and the selection of revision surgery plans have become important challenges in the current field of orthopedic and joint surgery. Reverse total shoulder arthroplasty (RTSA) has gradually become a treatment for cuff tear arthropathy since Grammont completed the biomechanical improvement. Effective methods for shoulder joint diseases, such as CTA and end-stage shoulder osteoarthritis, are still being developed, and current clinical research on the application of RTSA in revision after PHF internal fixation failure remains limited. Most existing studies are limited to small-sample, single-center retrospective analyses and lack support from high-quality multicenter randomized controlled trials (RCTs). In addition, the incidence and risk factors for complications after RTSA revision surgery remain unclear.

Objective

To explore the efficacy of reverse shoulder joint replacement surgery as a revision procedure in the treatment of failed internal fixation of proximal humeral fractures.

Methods

A retrospective analysis was conducted on 9 patients with failed plate internal fixation of proximal humeral fractures who were admitted from April 2018 to November 2023, including 2 males and 7 females. Age: 51 to 76 years old. All 9 cases underwent reverse shoulder joint replacement and revision surgery. Preoperative and postoperative systematic assessment of pain visual analogue scale (VAS), American shoulder and elbow surgeons' form (ASES) score, Constant-Murley shoulder score scale, University of California at Los Angeles UCLA score, disabilities of the arm, shoulder, and hand (DASH), shoulder pain and disability index Key indicators such as SPADI and joint range of motion were analyzed, and surgical complications were also analyzed.

Results

All 9 cases were followed up. At the last follow-up, compared with that before the operation, the Angle of flexion and elevation increased from (53.89±19.65) ° to (107.78±25.26) °. The external rotation Angle increased from (3.33±9.68) ° to (31.67±6.61) °. The internal rotation Angle increased from (25.00±13.23) ° to (57.22±9.05) °. The abduction Angle increased from (48.33±16.95) ° to (95.00±15.00) °. The UCLA score increased from (9.33±3.60) points to (22.78±6.39) points. The Constant-Murley shoulder joint score increased from (23.44±5.70) points to (61.56±18.75) points. The ASES score increased from (34.11±9.66) points to (74.44±18.80) points. The DASH score decreased from (65.55±9.13) points to (31.73±11.05) points. The SPADI score decreased from (57.34±14.05) points to (23.77±16.35) points. The VAS score decreased from (5.00±1.73) points to (1.11±2.26) points. Furthermore, the differences in each score were statistically significant (P < 0.05). One case presented with aggravated postoperative pain. One case had a humeral shaft fracture during the operation.

Conclusion

Reverse shoulder joint replacement, as a revision for failed internal fixation of proximal humeral fractures, has reliable efficacy and good clinical application value.

表1 9例患者术前一般资料
图1 患者,女,63岁,右PHFs内固定术后肱骨近端骨不连,行RTSA 图A-B:术前DR、CT示PHFs内固定后改变,肱骨头变形,骨折线仍可见;图C:术前查体示假瘫表现;图D:术中情况;图E:反肩术后DR示假体位置满意,未见明显并发症;图F:术后24个月随访患者患肢活动度较术前明显改善,疼痛缓解注:PHFs为肱骨近端骨折;RTSA为反向全肩关节置换术
图2 患者,男,71岁,右PHFs内固定术后可疑感染、肱骨头坏死,一期予内固定取出+骨水泥间隔器置入。监测4个月感染指标未见异常后,二期予反肩置换翻修手术 图A:术前DR示PHFs内固定后改变,骨折未愈合,骨折线仍可见,肱骨头坏死;图B:骨水泥制作的间隔器;图C:右肩固定取出术+间隔器置入术中情况;图D:一期术后DR示间隔器位置满意;图E-F:4个月后行间隔器取出+反肩置换翻修手术;图G:二期术后DR示反肩关节假体位置满意;图H-I:术后1年随访患者患肢活动度较术前明显改善,疼痛缓解注:PHFs为肱骨近端骨折
图3 患者,女,76岁,左PHFs内固定术后肱骨近端骨不连,行RTSA 图A-B:术前DR、CT示PHFs内固定后改变,肱骨头变形,骨折线仍可见;图C:术中将肱骨头脱位时发生肱骨中段骨折,予加长肱骨近端解剖钢板固定同时行反肩关节置换;图D:术后DR示反肩假体位置满意,解剖钢板固定在位;图E-F:术后6个月随访患者患肢活动度较术前改善,疼痛缓解注:PHFs为肱骨近端骨折;RTSA为反向全肩关节置换术
图4 术前与末次随访结果的配对连线、散点箱线图注:VAS为视觉模拟评分;UCLA为美国加州大学洛杉矶分校;ASES为美国肩肘外科医师协会;DASH为上肢功能障碍评定量表;SPADI为肩痛残疾指数
表2 患者术前与末次随访肩关节活动度(°,±s
表3 患者术前与末次随访VAS评分
表4 患者术前与末次随访肩关节功能评分(分,±s
表5 患者术前与末次随访肩关节残疾评分(分,±s
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