Proximal humeral fracture is a typical upper limb fracture in clinical practice, accounting for 5%-6% of the incidence of systemic fractures, which is the third most common fracture in the elderly population, and approximately 20% of proximal humeral fractures require surgical treatment. With the advent of the aging society, the incidence of proximal humerus fracture is increasing. In patients over 65, the incidence of proximal humeral fractures increases to 10%. Perioperative complications are noteworthy. Deep vein thrombosis (DVT) is the most common complication, likely leading to pulmonary embolism and increasing hospitalization costs. In recent years, many clinical studies have suggested that the incidence of DVT in Asia has shown a significant upward trend, which is directly related to the increased attention paid by clinicians and patients to DVT, so the discovery rate of DVT has increased yearly. According to Jang's research, the annual incidence of DVT in Asian populations shows a significant upward trend, especially in people over 60. Clinical studies in other parts of Asia also support this phenomenon. Although orthopedic surgeons routinely administer drug anticoagulation prevention to orthopedic inpatients at risk of DVT, thrombus still occurs in many patients. Perioperative thrombus in lower limb fractures has received much attention, especially in the distal femur, femoral shaft, and peri-hip fractures. However, there are few studies on perioperative thrombosis of upper extremity fractures, especially proximal humeral fractures.

To investigate the related factors of deep venous thrombosis in patients with proximal humeral fracture.

We prospectively included 126 patients with proximal humeral fractures admitted to Tianjin Hospital from January 2021 to January 2022. The baseline data and relevant laboratory indicators of these patients were collected. The incidence of deep vein thrombosis in patients with proximal humerus fracture was counted, and the related factors inducing deep vein thrombosis were analyzed.

Deep venous thrombosis occurred in 40 of 126 patients, and the incidence was 31.7%. The ages ranged from 18 to 83, with an average age of 58.9±15.4. The Logistic regression model results showed that high BMI and old age were the risk factors of deep venous thrombosis in patients (OR>1, P<0.05) .

Patients with proximal humeral fractures have a high risk of deep venous thrombosis. High BMI and old age are the risk factors of deep venous thrombosis in patients with proximal humerus fracture.